Dexamethasone and Dexmedetomidine as an Adjuvant to Spinal Anesthesia for Elective Caesarean Sections

Not Applicable

• Conditions: Pain, Postoperative
• Interventions: Drug: Intrathecal dexamethasone; Drug: Intrathecal dexmedetomidine

• Registration Number: NCT04697745
• Lead Sponsor: Benha University

Brief Summary

The main objective of our study is to evaluate analgesic effect of intrathecal dexamethasone and dexmedetomidine in elective caesarean sections

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-01
• Study First Submitted: 2021-01-04
• Study First Submitted QC: 2021-01-05
• Last Update Submitted: 2021-01-05
• Study First Posted: 2021-01-06
• Last Update Posted: 2021-01-06
• Study Start: 2021-03-01
• Primary Completion: 2021-04-30
• Study Completion: 2021-05-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 44

Inclusion Criteria

• American Society of Anesthesiologists classII-III adult female patient (age :18 -40 years old )
• Elective cesarean section under spinal anaesthesia
• Gestational age > 37 weeks
• BMI less than 30 kg/m2

Exclusion Criteria

• Patient refusal
• unable to give consent
• age < 18 or > 40
• BMI more than 30 kg/m2
• known allergy to the study medication
• coagulopathies or on anticoagulant medications
• diabetic neuropathy
• patients with psychiatric disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
dexamethasone intrathecal	Intrathecal dexamethasone	-
dexmedetomidine intrathecal	Intrathecal dexmedetomidine	-

Primary Outcome Measures

Name	Time	Method
analgesic effect	Up to 24 hours after surgery	Duration of sensory block and time to first analgesic rescue .; .

Secondary Outcome Measures

Name	Time	Method
intraoperative complications	during surgery	Incidince of intraoperative shivering, nausea and vometing