Prolongation of pain relief after injection of two drugs, dexamethasone and dexmedetomidine mixed with local anaesthetic above lamina of spine : a comparative study in patients of spine surgeries.

Phase 4

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2024/07/070046
• Lead Sponsor: All India Institute of Medical Sciences Patna

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

ASA physical status I and II patients undergoing thoracolumbar spinal surgeries less than or equal to five segments.

Exclusion Criteria

ASA III or more

Allergy to the drugs

Coagulopathy

Infection at puncture site

Mental disorder, Communication failure, unable to discriminate

cutaneous pin prick.

Chronic use of analgesics, inability to operate PCA pump

Preexisting spinal cord disease prior lumbar spine surgery

BMI more than or equal to 30

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the time to first rescue analgesic requirement in postoperative period. <br/ ><br>Timepoint: Within 24 hours of postoperative period <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
Severity of pain during postoperative period <br/ ><br>measured through NRS scaleTimepoint: 1,2, 4, 6, 12, 24 hours;To evaluate additional intraoperative fentanyl consumption in all groups.Timepoint: From administration of block till the end of surgery;Total postoperative fentanyl consumptionTimepoint: within 24 hours of postoperative period