Study of comparison of efficacy of dexamethasone and dexmedetomidine to relieve pain after surgery by mixing with local anaesthetics in anterior chest wall nerves block in patient undergoing cardiac surgery
Phase 4
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary arteryHealth Condition 2: I060- Rheumatic aortic stenosisHealth Condition 3: I069- Rheumatic aortic valve disease, unspecifiedHealth Condition 4: I050- Rheumatic mitral stenosisHealth Condition 5: I059- Rheumatic mitral valve disease, unspecified
- Registration Number
- CTRI/2024/01/062035
- Lead Sponsor
- All India Institute of Medical Sciences, Patna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiology physical status : I - III
Patients posted for elective open heart surgery via median sternotomy.
Exclusion Criteria
1. Patient refusal
2. Hypersensitivity, or a history of LA allergies
3. Undergone emergent or redo surgeries
4. Cognitive dysfunction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of dexamethasone and dexmedetomidine as adjuvants in transversus thoracic muscle plane blocks for CTRI/2024/01/062035 cardiac surgery trial?
How does the analgesic efficacy of dexamethasone versus dexmedetomidine in transversus thoracic muscle plane blocks compare to standard-of-care opioids for I251 patients undergoing median sternotomy?
Which biomarkers predict differential analgesic response to dexamethasone or dexmedetomidine in I060 and I050 cardiac surgery patients per CTRI/2024/01/062035?
What adverse events are associated with dexamethasone/dexmedetomidine adjuvants in transversus thoracic muscle plane blocks for I069 and I059 patients in Phase IV trials?
Are there alternative adjuvants to dexamethasone and dexmedetomidine, such as clonidine or liposomal bupivacaine, that demonstrate superior analgesic outcomes in CTRI/2024/01/062035 cardiac surgery cohort?