The significance of hyperglycaemia in survivors of critical illness and potential mechanisms underlying development of type 2 diabetes

Not Applicable

Recruiting

• Conditions: Critical Illness; Type 2 Diabetes; Hyperglycaemia; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12614000449639
• Lead Sponsor: Dr Adam Deane

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Critical Illness-associated hyperglycaemia: HbA1c < 6.5%, blood glucose concentrations > 11.1 mmol/l for at least two consecutive readings during ICU admission
Normoglycaemic: HbA1c < 6.5%, fasted blood glucose concentrations remain < 7.1mmol/l and random concentrations remain < 11.1 mmol/l throughout ICU admission
Healthy volunteers: >18 years of age, sex and BMI will be used to match volunteers

Exclusion Criteria

Inability to give informed consent, current pregnancy, previous gestational diabetes, acute or chronic pancreatitis, medications known to affect glucose metabolism (e.g. steroids)

Study & Design

• Study Type: Observational
• Study Design: Not specified