iQuit in Practice

Not Applicable

Completed

• Conditions: Specialty: Primary Care, Primary sub-specialty: Public Health; UKCRC code/ Disease: Cancer/ Malignant neoplasms of respiratory and intrathoracic organs, Cardiovascular/ Pulmonary heart disease and diseases of pulmonary circulation, Respiratory/ Lung diseases due to external agents, Stroke/ Cerebrovascular diseases; Cancer

• Registration Number: ISRCTN44559004
• Lead Sponsor: niversity of Cambridge

Brief Summary

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32673255/ protocol (added 17/07/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-21
• Study Completion: 2019-10-31
• Last Update Posted: 11 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1452

Inclusion Criteria

1. Current smoker aged 16 - 75
2. Wants to quit and willing to attending for smoking cessation support at a GP practice
3. Owns a mobile phone and familiar with sending/receiving text messages
4. Able to read and understand English, and give informed written consent
5. Willing to set a quit-date within 14 days of starting the study
6. Not currently involved in another formal smoking cessation study

Exclusion Criteria

1. Not meeting the inclusion criteria
2. Their GP feels that it would not be appropriate for them to participate (e.g. severe complex additional health problems)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Self-reported abstinence from smoking for 6 months endorsed by biochemical verification measured 6 months after the participant’s quit date. Abstinence from smoking will be measured 6 months after the participant’s quit date using a questionnaire (sent by the research team) followed by biochemical verification. All participants that have stated in the questionnaire they have not smoked for 6 months will be sent a kit to collect a saliva sample. The sample will be analysed for cotinine (a nicotine metabolite). If the sample is positive for cotinine then the sample will also be assayed for anabasine to differentiate whether the cotinine has come from tobacco, E-Cig or NRT.

Secondary Outcome Measures

Name	Time	Method
1. Abstinence is measured using carbon monoxide (CO) testing at baseline and the routine follow-up 4-week appointment in the patient’s GP practice<br>2. Abstinence is measured through self-reporting using a questionnaire deigned for this study at 6 months (not biochemically validated) <br>3. Cost-effectiveness of the intervention is determined using a questionnaire at 6 months post quit date will determine NHS costs accumulated during the previous 6 months through questions on GP visits and medications prescribed, including NRTs