Prospective trial for evaluation of potential heart dose reduction using deep inspiration breath-hold in radiotherapy of left-sided breast cancer

Not Applicable

• Conditions: C50.9; Breast, unspecified

• Registration Number: DRKS00010929
• Lead Sponsor: C-RAD AB

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-12-31
• Study Start: 2016-08-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 17

Inclusion Criteria

left-sided breast cancer
indication for adjuvant whole breast irradiation

Exclusion Criteria

informed consent not possible
breath-hold of 20 seconds not possible

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
significant heart dose reduction in planning and Treatment checked by heart inside Treatment field and further Parameters like heart mean and max dose as well as max LAD (left anterior descending artery) dose.

Secondary Outcome Measures

Name	Time	Method
lung dose assessment (mean lung dose, left lung V20Gy), target dose coverage (V95%), clinical feasability<br><br>Follow-Up using Lent-Soma Criteria<br><br>Follow-Up for cardiac toxicity (10-20 years) no endpoint of this study