Copeptin as a possible predictor of developing diabetes insipidus following transsphenoidal pituitary surgery

Withdrawn

• Conditions: ADH deficiency/or resistance; 10021112

• Registration Number: NL-OMON41983
• Lead Sponsor: Inwendige Geneeskunde/Endocrinologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

-adult patiënts scheduled for endoscopic transnasal pituitary surgery

Exclusion Criteria

- patients <18 y old
- wilsonbekwamen
- patients with pre-existent diabetes insipidus

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The difference in copeptin levels between patients who develop DI and those who<br /><br>do not at several timepoints following surgery.<br /><br>We will also determine a cut-off level of copeptin which can be used to predict<br /><br>development of DI post surgery.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>