Recognizing patients with (a higher risk of) endometrial cancer; the rol of fat distribution and inflammation in the origin of endometrial cancer, a study that focuses on prevention and predictio

Recruiting

• Conditions: cancer of the womb; Uterine cancer; 10038594

• Registration Number: NL-OMON52042
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

Cases: Subjects with endometrial cancer/hyperplasia with atypia, who are
planned for hysterectomy with bilateral salpingo-oophorectomy.
Controls: Subjects who are planned for bilateral salpingo-oophorectomy without
malignancy and are older than 40

Exclusion Criteria

Malignancy 5 years prior to inclusion (basal cell carcinoma excluded)
Use of systemic hormonale therapy the past 12 months
inadequate knowledge of the Dutch language
Contra-indication for ct-scan

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Hormone levels and inflammation markers after BSO depending on BMI</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Effect of fat distribution on hormone levels and inflammation markers<br /><br>Effect of BSO on subjects complaints (depending on BMI)</p><br>