Influence of soluble corn fibre on markers of immunity and inflammatio

Not Applicable

• Conditions: People aged 60 + years living in the community; Not Applicable

• Registration Number: ISRCTN15979195
• Lead Sponsor: niversity of Southampton

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-17
• Last Update Posted: 15 April 2024
• Study Completion: 2025-01-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

1. Community-dwelling males and females aged 60 years and older
2. Body mass index of 18.5-30 kg/m2
3. Have regular bowel movements
4. Willing to adhere to the study protocol
5. Able to provide written informed consent

Exclusion Criteria

1. Living in a care or nursing home
2. Diagnosed with diabetes or other metabolic and endocrine disorders
3. Presence of active gastrointestinal disease (coeliac disease, Crohn’s disease, diagnosed IBD etc.), autoimmune disease, or inflammatory disease (lupus, rheumatoid arthritis, multiple sclerosis)
4. Use of prescribed medicine to control inflammation (e.g. non-steroidal anti-inflammatory drugs; NSAIDs) or regular use of over-the-counter NSAIDs
5. Use of dietary supplements (will allow a 4-week washout period)
6. Use of probiotic drinks or yoghurts (will allow a 4-week washout period)
7. Have extreme habitual fibre intake (lower than 10 g per day or higher than 30 g per day) based on a validated fibre screening tool
8. Blood donation in the previous 3 months.
9. Participation in any other clinical trial in the previous 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified