Brain stimulation targeting neurocognition and social functioning in schizophrenia
Not Applicable
- Conditions
- Health Condition 1: null- schizophrenia
- Registration Number
- CTRI/2015/01/005448
- Lead Sponsor
- DEPARTMENT OF BIOTECHNOLOGY MINISTRY OF SCIENCE AND TECHNOLOGY UNDER INCRE FELLOWSHIP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
1. Diagnosis of Schizophrenia (F20.0-F20.9) according to
ICD-10-DCR
2. Patients on a stable dose of antipsychotic medication
3. Patients of either sex aged between 18-60 years.
4. Right handed, normotensive patients.
5. Patients giving written informed consent.
6. Screened eligible for rTMS.
Exclusion Criteria
1. Current neurological or any comorbid psychiatric disorders.
2. History of substance abuse (Except nicotine and caffeine) in the
past one month.
3. History of epilepsy, significant head injury or any neurosurgical
procedure.
4. Subjects with cardiac pacemakers or other metal parts in the
body.
5. Subjects who have received ECT in past 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Working Memory, Emotion Recognition and Social FunctioningTimepoint: Baseline and at the end of 2 weeks of post rTMS intervention
- Secondary Outcome Measures
Name Time Method spontaneous gamma oscillatory activity (GOA) and GOA evoked by online working memory and emotion recognition tasks and psychopathology scores PANSSTimepoint: Baseline and at the end of 2 weeks of post rTMS intervention <br/ ><br>