Comparison of Triamterene-hydrochlorothiazide and Hydrochlorothiazide in refractory edema

Phase 1

Recruiting

• Conditions: Systolic and diastolic heart failure.; Combined systolic (congestive) and diastolic (congestive) heart failure; I50.4

• Registration Number: IRCT20111206008307N37
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with systolic and diastolic heart failure and refractory edema
GFR > 30

Exclusion Criteria

Renal dysfunctin (creatinine clearance of <30 ml/min)
History of end-stage renal failure or dialysis
Cardiogenic shock
Acute myocardial infarction
Hypoalbuminemia
Any contraindications for Triamterene-Hydrochlorothiazide and Hydrochlorothiazide
Patients who are not satisfied

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fluid Input/Output. Timepoint: Daily from admission day to discharge day. Method of measurement: Urine bag.;Measurement of Na and K. Timepoint: Daily from admission day to discharge day. Method of measurement: Laboratorial.;Edema. Timepoint: Daily from admission day to discharge day. Method of measurement: Physical examination.