Patient Preference Study: Standard of Care Versus Once-daily Trientine Tetrahydrochloride
Phase 2
Not yet recruiting
- Conditions
- Wilson's Disease
- Interventions
- Drug: New TETA 4HCl FormulationDrug: Standard of Care
- First Posted Date
- 2025-06-08
- Last Posted Date
- 2025-07-03
- Lead Sponsor
- Orphalan
- Target Recruit Count
- 10
- Registration Number
- NCT07010575
Study Comparing Once Daily Dose of 900mg of TETA 4HCL Against Cuprior® (450mg Trientine Base, Twice Daily).
Phase 1
Completed
- Conditions
- Wilson's Disease
- Interventions
- Drug: 900mg TETA 4HCl Once Daily FormulationDrug: 900mg TETA 4HCl Cuprior®
- First Posted Date
- 2023-11-13
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- Orphalan
- Target Recruit Count
- 24
- Registration Number
- NCT06128954
- Locations
- 🇬🇧
Richmond Pharmacology Ltd, London, United Kingdom
Real World Evidence Study in Subjects With Wilson's Disease
Active, not recruiting
- Conditions
- Wilson Disease
- Interventions
- Diagnostic Test: NCC-Sp Assay
- First Posted Date
- 2023-03-24
- Last Posted Date
- 2025-07-03
- Lead Sponsor
- Orphalan
- Target Recruit Count
- 50
- Registration Number
- NCT05783687
- Locations
- 🇺🇸
UC Davis Midtown Ambulatory Care Centre, Sacramento, California, United States
🇺🇸Yale University School of Medicine, New Haven, Connecticut, United States
🇺🇸University of Miami, Miami, Florida, United States
International Wilson's Disease Patient Registry (iWilson Registry)
Recruiting
- Conditions
- Wilson's Disease
- First Posted Date
- 2022-02-15
- Last Posted Date
- 2025-07-03
- Lead Sponsor
- Orphalan
- Target Recruit Count
- 500
- Registration Number
- NCT05239858
- Locations
- 🇧🇪
University Hospital Leuven, Leuven, Belgium
🇫🇷Hospices Civils de Lyon, Bron, Auvergne-Rhone-Alpes, France
🇫🇷HF Adolphe de Rothschild, Paris, Île-de-France, France
Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease
Phase 3
Completed
- Conditions
- Wilson Disease
- Interventions
- First Posted Date
- 2018-05-30
- Last Posted Date
- 2025-07-02
- Lead Sponsor
- Orphalan
- Target Recruit Count
- 77
- Registration Number
- NCT03539952
- Locations
- 🇺🇸
Yale University School of Medicine, New Haven, Connecticut, United States
🇧🇪KU Leuven, Department of Clinical and Experimental Medicine, Leuven, Belgium
🇧🇷Hospital Nossa Senhora das Graças (HNSG), Curitiba, Brazil