Virtual reality augmented exercise in multiple sclerosis patients

Completed

Conditions: Multiple sclerosis
Nervous System Diseases

Registration Number: ISRCTN13924231

Lead Sponsor: Teesside University (UK)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 66

Inclusion Criteria

1. Men and women
2. Aged 18-65 years
3. A clinical diagnosis of MS
4. Expanded Disability Status Scale (EDSS) score of one to six (Kurtzke, 1983)
5. Able to read and comprehend written and spoken English (regrettably validated translations of the outcome measure questionnaires are not available)

Exclusion Criteria

1. Currently in acute exacerbation and/or has relapsed within the last three months
2. Diagnoses of any other condition affecting the central nervous system
3. Any musculoskeletal injury or condition for which a health professional has advised the person to refrain from undertaking moderate physical activity
4. Any doubt of ability to give informed consent
5. Currently receiving physical therapy aimed at improvements in fitness and balance
6. Any allergy to conductance gel and/or hypoallergenic tape used during electromyography

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Standing balance during quiet unipedal (standing on one foot) and bipedal (standing on two feet) stance recorded by Kistler™ force plate<br>2. Dynamic balance during sit-to-stand and ground reaction force<br>3. Temporal distance parameters of gait stride length, cadence, velocity, single and double limb support time<br>4. Measures of technology acceptance and exercise experience questionnaires

Secondary Outcome Measures

Name	Time	Method
1. Muscle activity: relationships between electromyography (EMG) and measures of static and dynamic postural stability<br>2. Self reported walking ability: differences in MSWS12<br>3. Self reported function: differences in WHODAS II, and pain questionnaires<br>4. Self reported exertion: Rating of Perceived Exertion