The effect of preoperative polyunsaturated fatty acid use on perioperative inflammatory response

Not Applicable

Recruiting

• Conditions: perioperative inflammatory response; postoperative pain; Anaesthesiology - Other anaesthesiology; Inflammatory and Immune System - Normal development and function of the immune system

• Registration Number: ACTRN12623000051640
• Lead Sponsor: T.R. Necmettin Erbakan University Scientific Research Projects Coordinatorship

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-01-17
• Last Update Posted: 23 January 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

Between 1 November 2022 and 31 January 2023,
physical status is ASA II according to the classification of the American Society of Anesthesiology (ASA),
over 18 years,
using fish oil supplement with at least 500 mg of omega3 content,
omega-3 pufa users (for the omega-3 group)
omega-3 pufa non-users (for the control group)

Exclusion Criteria

Patients with poor orientation and cooperation,
serious psychiatric patients
emergency cases,
gestational diabetes,
gestational hypertension,
preeclampsia,
eclampsia,
patients with a history of cardiac arrhythmia and heart failure,
Patients using fish oil supplement preparation with less than 500 mg or higher omega3 content,
patients with chronic smoking, alcohol or drug addiction
patients who do not agree to volunteer

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
perioperative inflammatory response assessed by interleukin-6 levels in serum[1 hour before the operation,<br>6 hours after the operation,<br>24 hours after the operation.];perioperative inflammatory response assessed by interleukin-10 levels in serum[1 hour before the operation,<br>6 hours after the operation,<br>24 hours after the operation.];perioperative inflammatory response assessed by C-reaktive protein levels in serum[1 hour before the operation,<br>6 hours after the operation,<br>24 hours after the operation.]

Secondary Outcome Measures

Name	Time	Method
postoperative pain assessed numeric rating score[postoperative period 6 ours after the operation and 24 ours after the operation.];hospital stay duration[postoperative period at stay hospital]