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Clinical Trials/NCT06178276
NCT06178276
Recruiting
Not Applicable

Investigation of Neurophysiological Functioning During Oral Comprehension Task. An Exploratory Study in Second Language (Italian) Learning in French Students Using Autonomic and Cerebral Investigation

University Hospital, Grenoble1 site in 1 country70 target enrollmentFebruary 14, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Learning
Sponsor
University Hospital, Grenoble
Enrollment
70
Locations
1
Primary Endpoint
Sympathetic activity
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The oral comprehension (OC) of a second language (L2) involves different cognitive processes, specially during the learning phase. This study aims at investigating the neurophysiological functioning of different steps involved in this oral understanding.

Detailed Description

Here, the investigators seek for the different neurophysiological processes involved in OC according to the level of understanding (2 levels) and its different phases (fluid, hindered and metacognitive feedback). This study therefore requires three different research methodologies : 1. an interactive system dedicated to the boundary delimitations of obstacles during OC 2. an investigation of the autonomic nervous system responses (measurement of electrodermal activity and heart rate variability) that will likely occur differently during different phases of the OC process 3. an investigation of the central responses (through fMRI technique), coupled with autonomous responses, that will identify the different neural networks in the different stages of the OC process.

Registry
clinicaltrials.gov
Start Date
February 14, 2024
End Date
February 2026
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Grenoble
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • French learner in Italian language
  • right-handed
  • affiliated to French social security
  • informed consent signed

Exclusion Criteria

  • pregnant woman
  • audiologic pathology impacting the capacity of hearing
  • neurologic or psychiatric pathology that may interfere with oral comprehension
  • learning disability (for instance: dyslexia)
  • contra-indication to MRI and to EDA acquisition

Outcomes

Primary Outcomes

Sympathetic activity

Time Frame: up to 3 months following the language profile completion

ElectroDermal Activity (EDA) measured in µS

Secondary Outcomes

  • Interaction between sympathetic activity and brain activity(up to 6 months following the acquisition of language profile)
  • Activated brain regions demonstrating brain activity(up to 6 months following the language profile completion)
  • Parasympathetic activity(up to 3 months following the language profile completion)
  • Correlations between sympathetic and parasympathetic activity(up to 3 months following the language profile completion)
  • Interaction between parasympathetic activity and brain activity(up to 6 months following the acquisition of language profile)
  • Linguistic evaluation(up to 1 month following the acquisition of language profile)
  • Cognitive evaluation of executive functions(up to 1 month following the acquisition of language profile)
  • Cognitive evaluation of short term memory(up to 1 month following the acquisition of language profile)

Study Sites (1)

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