Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Comparison of amounts of HOXA10 and HOXA11 expressed before and after polypectomy
研究概览
简要总结
The aim of this study is to measure the expression of HOXA10 and HOXA11 in the endometrium of infertility patients with an endometrial polyp before and after polypectomy. HOXA10 and HOXA11 are well-established markers of implantation. It is uncertain as to whether an endometrial polyp interferes with embryo implantation. A higher expression of HOXA10 and HOXA11 after polypectomy can indicate that endometrial polyp does interfere with embryo implantation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Infertile women with endometrial polyp
排除标准
- •Endometriosis
- •Polycystic ovary syndrome
- •Hydrosalpinx
- •Sub-mucus myoma
- •Women who have taken hormonal therapy in the preceding month
研究组 & 干预措施
HOXA10 and HOXA11 Expression Before Polypectomy
A biopsy will taken in infertility patients with endometrial polyp before polypectomy
干预措施: Endometrial biopsy (Procedure)
HOXA10 and HOXA11 Expression After Polypectomy
A biopsy will taken in infertility patients with endometrial polyp 1-3 months after polypectomy
干预措施: Endometrial biopsy (Procedure)
结局指标
主要结局
Comparison of amounts of HOXA10 and HOXA11 expressed before and after polypectomy
时间窗: Four months
次要结局
未报告次要终点