Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

Completed

• Conditions: Microbial Colonization; Cholangiopancreatography, Endoscopic Retrograde; Common Bile Duct Calculi

• Registration Number: NCT03490383
• Lead Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Brief Summary

In this study, investigators will investigate the microbiota of bile in common bile duct stone participants. Three key questions are of concern. The first one is whether there is bacteriria in bile in participants without common bile duct stone. The second one is whether the microbiota of bile is similar with that of gut mucosa in common bile duct stone participants. The third one is whether the bacteria in bile of common bile participants with intact papillar is the same as that of participants underwent sphinctomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-16
• Study First Submitted: 2018-03-14
• Study First Submitted QC: 2018-04-05
• Study First Posted: 2018-04-06
• Primary Completion: 2023-04-01
• Study Completion: 2023-04-01
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-26
• Last Update Posted: 2023-10-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• CBD tumor or CBD calculi

Exclusion Criteria

• contraindication for ERCP

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
microbiota in bile	intraoperative	16s RNA

Trial Locations

Locations (2)

Shanghai Municipal Hospital of Traditional Chinese Medicine; 🇨🇳 Shanghai, China

Shang General Hospital; 🇨🇳 Shanghai, China