The Natural History of Geographic Atrophy Progression (GAP) Study
Terminated
- Conditions
- Age-Related Macular DegenerationGeographic Atrophy
- Registration Number
- NCT00599846
- Lead Sponsor
- Alcon Research
- Brief Summary
The objective of the 18-month trial is to evaluate the natural history of geographic atrophy by assessing the rate of progression of the geographic atrophic lesion over time.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
- Clinical diagnosis of geographic atrophy secondary to age-related macular degeneration with no CNV lesion.
Exclusion Criteria
- Age related
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method GA progression rate using fundus autofluorescence From baseline
- Secondary Outcome Measures
Name Time Method GA progression rate using fundus photography From baseline
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms drive geographic atrophy progression in NCT00599846 Age-Related Macular Degeneration study?
How does the natural history of geographic atrophy in NCT00599846 compare to standard-of-care treatment outcomes for AMD?
What biomarkers are associated with geographic atrophy progression in the NCT00599846 observational study?
What adverse events are reported in geographic atrophy patients during the NCT00599846 18-month follow-up?
What are the potential therapeutic targets identified in NCT00599846 for geographic atrophy in Age-Related Macular Degeneration?
Trial Locations
- Locations (1)
Houston
🇺🇸Houston, Texas, United States
Houston🇺🇸Houston, Texas, United States