NCT02278497Unknown不适用
Assessment of Coronary Flow Reserve by PET-H215O and FFR in Patients Suspected of Coroanry Artery Disease. a Comparative Study With Dynamic Acquisition Using CZT Camera and 99mcTc-mibi.
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Assess myocardial coronary reserve by cardiac CZT camera and Tcmibi comparing with the PET and the water marked during coronary FFR (Flow Fraction Reserve)
研究概览
简要总结
The study will assess coronary flow reserve by PET-H215O and FFR in patients suspected of coroanry artery disease. This a comparative study with dynamic acquisition using CZT camera and 99mcTc-mibi. 20 patients will have those measurements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient between 18 and 80 years
- •Suspected coronary disease and / or coronary syndrome patient ST-
- •Patient who has been informed of the study and has given his informed consent
- •Patient affiliated to a social security system.
排除标准
- •Patient having no coronary disease at coronary angiography with FFR on the 3 main epicardial arteries (absence of ≥ 50% stenosis of at least one artery)
- •Delay of Care grater than 30 days between the PET and SPECT imaging and the diagnostic coronary angiography
- •Patient with a recent history of myocardial infarction and STEMI, unstable angina
- •Patient with extra-cardiac disease whose prognosis can interfere with the treatment decision
- •Pregnant or lactating women
- •Patient allergic to contrast products during coronary angiography
- •Patient with MDRD clearance les than 60 ml / min
- •Patient Under guardianship, or unable to understand the purpose of the study
结局指标
主要结局
Assess myocardial coronary reserve by cardiac CZT camera and Tcmibi comparing with the PET and the water marked during coronary FFR (Flow Fraction Reserve)
时间窗: baseline
次要结局
未报告次要终点
研究者
研究点 (2)
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