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Clinical Trials/NCT04008719
NCT04008719
Completed
Not Applicable

Predictivity of Attention Test and Executive Functions After Stroke to Predict Depression 3 Months After Stroke.

Centre Hospitalier St Anne1 site in 1 country74 target enrollmentMay 16, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post-stroke Depression
Sponsor
Centre Hospitalier St Anne
Enrollment
74
Locations
1
Primary Endpoint
Post stroke depression
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.

Detailed Description

1. Baseline visit: after neurologic stability, 14 days or less after stroke and before discharge. 2. First assessment : 1. Neurologic data: morphologic data (MRI of the brain), stroke severity (NIHSScore), aphasia assessment (Boston Diagnostic Aphasia Examination) if NIHS verbal score ≥1, hemineglect assessment (Bells test). 2. Personal data assessment : i. Socio demographic : age, gender, marital status, employment, level of education ii. Medical history: medical treatments, psychiatric and non psychiatric history. c. Psychiatric assessment i. Mini International Neuropsychiatric Interview - depression ii. Beck Depression Inventory iii. Clinical Global Impression iv. Standardized Assessment of Personality - Abbreviated Scale (SAPAS) v. Fageström-C vi. Alcohol Use Disorders Identification Test (AUDIT-C) d. Cognitive assessment: i. Verbal memory : Dubois's five words ii. Clock drawing test iii. D2test (computerized) iv. Verbal fluency (Cardebat) v. Working memory (digit span WAIS 3) vi. Brixton (computerized) 3. Assessment 3 months after the first assessment. Phone call and psychiatric assessment: MINI depression, Beck Depression Inventory. Barthel index and Quality of Life assessment.

Registry
clinicaltrials.gov
Start Date
May 16, 2017
End Date
September 30, 2019
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Centre Hospitalier St Anne
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 18 or more
  • Ischemic or hemorragic stroke, diagnosed with radiology : cerebral CT or MRI, 14 days or less after stroke
  • Signed Consent
  • Social insurance regime affiliation

Exclusion Criteria

  • No possibility of follow-up
  • No French-speaker : insufficient command of French
  • Deprivation of liberty : judicial or administrative decision
  • D2 test assessment impossibility
  • Aphasia with major disorder of the understanding (Boston \<8)
  • Antidepressant treatment during stroke
  • Depression during stroke
  • protected people

Outcomes

Primary Outcomes

Post stroke depression

Time Frame: 3 months

Whether or not a post-stroke depression occurs. occurrence of post-stroke depression assessed with Mini International Neuropsychiatric Interview (MINI), subscale depression .

Secondary Outcomes

  • Post-stroke depression population characterization(1 day)

Study Sites (1)

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