DRKS00000264已完成不适用
Investigation of response of glioblastomas to cytotoxic drugs in vitro (ivt Study) - ivt
niversitätsklinikumRheinisch-Westfälische Technische Hochschule Aachen0 个研究点目标入组 24 人开始时间: 2009年11月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 75 Years（—）
- 性别
- All
入选标准
- •new radiological diagnosis of a malignant glioma (MRT based)
- •indication for surgical resection
- •Karnofsky index of at least 70%
- •no principal denial of chemotherapy
- •no serious hematological, liver, kidney abnormalities precluding chemotherapy
- •written informed consent of the patient
排除标准
- •younger than 18 or older than 75 years
- •preoperative a/o intraoperative verification of a pathology, incompatible with a malignant glioma (WHO grade III/IV)
- •no histologically confirmed glioblastoma
- •tumor infiltrates areas of the brain that preclude an adequate radiation dose
- •prior tumor surgery or other treatment
- •Karnofsky index of less than 70%
- •severe cardiovascular disease
- •severe hematological impairment, kidney a/o liver insufficiency which preclude chemotherapy
- •serious infection
- •basic unwillingness to receive chemotherapy
- •other malignancies (except basalioma)
- •pregnancy or lactation
- •women in childbearing age if contraception cannot be warranted
- •dementia or other mental state which precludes comprehension of therapy and hence, informed consent
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