Evaluation of the effect of very small stem cells from peripheral blood on the results of IVF cycles in diminished ovarian reserve patients.

Phase 1

Recruiting

Conditions: infertility due to diminished ovarian reserve.
Female infertility associated with anovulation
N97.0

Registration Number: IRCT20230420057968N1

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 15

Inclusion Criteria

Women with a calendar age of 40 and under
Women diagnosed with diminished ovarian reserve
Women with a history of IVF cycle failure in the last year
The infertile couple should be fully satisfied with the procedure
Couples who want to repeat the IVF cycle three months after this treatment

Exclusion Criteria

Dissatisfaction of the infertile couple
Women with autoimmune diseases
Women with endometriosis
Women with ovarian cancer
Women with breast cancer
Women with poly cystic ovarian syndrome
Women with infectious diseases such as hepatitis and acquired immunodeficiency virus
Women with ovarian failure secondary to hypothalamic and pituitary disorders
A couple diagnosed with recurrent miscarriage
A couple do not give consent

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The number of oocytes obtained in the IVF cycle after ovarian stem cells therapy. Timepoint: Before the start of the intervention and after 3 months of ovarian stem cells therapy in IVF cycle again. Method of measurement: Counting under the microscope.;The total number of embryos obtained in the IVF cycle after ovarian stem cells therapy. Timepoint: Before the start of the intervention and after 3 months of ovarian stem cells therapy in IVF cycle again. Method of measurement: Counting under the microscope.

Secondary Outcome Measures

Name	Time	Method
Evaluation the number of clinical pregnancies in the IVF cycle after ovarian tuberculosis therapy. Timepoint: 3 months after ovarian stem cells therapy in the IVF cycle again in terms of clinical pregnancy( seeing the heartbeat of the fetus in sonography). Method of measurement: Pregnancy blood test and transvaginal ultrasound.