Clinical observation on the therapeutic effect of 'three-part acupoint combination' combined with Aili eye drops in the treatment of perimenopausal dry eye syndrome.

Phase 1

Recruiting

• Conditions: dry eye disease

• Registration Number: ITMCTR2000003938
• Lead Sponsor: Shanghai General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

(1) Meet the above diagnostic criteria of perimenopausal dry eye with deficiency of liver and kidney Yin;
(2) If the western medicine eye drops are used for treatment before enrollment, the drug should be stopped for at least three weeks or more; in addition, the patient has not participated in other therapies or other clinical studies within three months;
(3) Non-allergic constitution;
(4) Voluntary participation and signing of informed consent.

Exclusion Criteria

(1) Patients with other eye diseases, such as congenital tear deficiency, lacrimal duct obstruction, severe trachoma, keratopathy, conjunctival scarring, conjunctival lesions and other eye diseases, and subjects undergoing eye surgery;
(2) Combined with dry mouth, joint pain and dry skin, considered as sjogren's syndrome caused by dry eyes;
(3) Subjects during pregnancy and lactation;
(4) Subjects with severe systemic diseases, such as cardiovascular and cerebrovascular diseases, severe liver and kidney dysfunction, and coagulation dysfunction;
(5) Subjects with mental disorders or psychological disorders who cannot cooperate with the treatment and study;
(6) Contact lens wearer.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
BUT;FL;Schirmer test;

Secondary Outcome Measures

Name	Time	Method
sex hormone;