Outcome of Acanthamoeba keratitis with adjuvant oral Miltefosine.
Not Applicable
Suspended
- Conditions
- Health Condition 1: B601- Acanthamebiasis
- Registration Number
- CTRI/2020/11/029120
- Lead Sponsor
- V Prasad Eye Instituta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with age more than 18 years
2.Microbiologically proven Acanthamoeba keratitis
3.Patients willing to participate and follow up.
Exclusion Criteria
1.Patients with age less than 18 years
2.Pregnant and lactating females
3.Patients who are likely to be pregnant are relative contraindicated.
4.Patient not willing to participate and follow up
5.Patients with known allergy to Miltefosine
6.Patients with epithelial or sub epithelial keratitis with only anterior stroma involvement with less than 4 mm.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BCVA, Healing time, Number of corneal ulcers responded on medical treatmentTimepoint: 0 week, 1 week, 2 week , 1 month, 3 month, 6 months
- Secondary Outcome Measures
Name Time Method umber of patients needed glue or undergone therapeutic Penetrating keratoplasty (TPK) for worsening of infection.Timepoint: It will be observed as a pilot trial of 10 patients for 6 months and later continued for 2 years. we will perform analysis of these cases after 6 months <br/ ><br>1 week, 1 month, 2 months and 4 months.