Effect of dexmedetomidine plus ketamine on postoperative analgesia in patients undergoing infra umbilical surgeries under spinal anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
研究概览
简要总结
This study evaluates the effect of intravenous dexmedetomidine combined with ketamine on postoperative analgesia in patients undergoing infraumbilical surgeries under spinal anaesthesia. Spinal anaesthesia has limited duration, and commonly used intrathecal adjuvants have notable side effects. Dexmedetomidine and ketamine, when used together, may provide synergistic analgesia with better haemodynamic stability. This prospective, randomized, double-blind, placebo-controlled study includes 80 ASA I–II patients aged 18–65 years. Primary outcomes include duration of analgesia, postoperative pain scores, and rescue analgesic requirement, while secondary outcomes assess haemodynamics, sedation, patient satisfaction, and complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients age 18 to 65 years of either sex belonging to ASA physical status 1/2 scheduled for infra umbilical abdominal surgery under subarachnoid block.
排除标准
- •Refusal to participate.
- •Contraindication to spinal anaesthesia Ischemic heart disease recent head injury or neuro psychiatric illness Known allergy to the drugs being used Pregnancy Surgery duration, less than one hour.
研究者
Dr Preeti Gehlaut
PGIMS Rohtak