EFFECTS OF BLOOD FLOW RESTRICTION TRAINING ON QUADRICEPS MUSCLE STRENGTH AND BIOCHEMICAL PARAMETERS AMONG INDIVIDUALS WITH TYPE 2 DIABETES MELLITUS: A RANDOMIZED CONTROLLED TRIAL
Trial Snapshot
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Quadriceps muscle strength,
Study Overview
Brief Summary
Blood flow restriction training (BFRT) involves partially occluding blood flow to exercising muscles, offering a promising alternative for individuals with type 2 diabetes. This study aims to compare BFRT with resistance training in improving quadriceps strength and biochemical parameters in individuals with type 2 diabetes. Participants will be randomly assigned to either BFRT or resistance training groups for 4 weeks. Outcome measures include quadriceps strength, HbA1C, and lipid profiles. BFRT may offer effective muscle strengthening and metabolic benefits for individuals with type 2 diabetes.
Patients will be recruited after getting CTRI registration no.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 35.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Atleast 2 years history of Type 2 Diabetes HBA1C more than 6 Non Smoker & Non Alcoholic.
Exclusion Criteria
- •Respiratory problem, Severe complications of diseases(peripheral diabetic neuropathy, cardiovascular, renal, visual, cerebral) Neurological disorders, Musculoskeletal disorders.
Outcomes
Primary Outcomes
Quadriceps muscle strength,
Time Frame: Baseline & After intervention of 4 weeks (3 days per week)
Haemoglobin A1c,
Time Frame: Baseline & After intervention of 4 weeks (3 days per week)
Low-density lipoproteins, High-density lipoproteins, Very low-density lipoproteins, Triglycerides, Total cholesterol
Time Frame: Baseline & After intervention of 4 weeks (3 days per week)
Secondary Outcomes
No secondary outcomes reported
Investigators
Arghya Mondal
Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation