K Lung cancer Screening pilot trial (UKLS)

Not Applicable

Completed

• Conditions: ung cancer; Cancer; Malignant neoplasm of bronchus and lung

• Registration Number: ISRCTN78513845
• Lead Sponsor: Royal Liverpool & Broadgreen University Hospital Trust (UK)

Brief Summary

2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26173719 results 2016 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26645413 results 2016 Results article in http://www.ncbi.nlm.nih.gov/pubmed/27224642 results 2016 Results article in http://www.ncbi.nlm.nih.gov/pubmed/27471048 results 2017 Results article in http://www.ncbi.nlm.nih.gov/pubmed/28710339 results 2021 Results article in https://doi.org/10.1016/j.lanepe.2021.100179 (added 30/09/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2012-12-31
• Study Start: 2014-01-20
• Last Update Posted: 11 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 4055

Inclusion Criteria

1. Risk criteria based on the LLP Risk Prediction Model (includes age, sex, smoking duration, history of previous pneumonia, history of previous cancer, family history [early/late onset], exposure to asbestos - algorithm)
2. Males and females aged between 50 to 75 years old
3. Fully informed written consent given

Exclusion Criteria

1. Unable to give consent
2. Co-morbidity which would unequivocally contraindicate either screening or treatment if lung cancer were detected
3. A CT scan of the chest performed within one year of the invitation to be screened
4. Any condition precluding written informed consent
5. Inability to lie flat
6. Weight greater than 200 kg (too large for CT scanner)

Study & Design

• Study Type: Interventional
• Study Design: Not specified