Evaluation of the Anti-inflammatory Effect of Atorvastatin on Patients with Rheumatoid Arthritis
Phase 2
- Conditions
- Rheumatoid Arthritis.XIII Diseases of the musculoskeletal system and connective tissue
- Registration Number
- IRCT2016010425816N1
- Lead Sponsor
- Vice Chancellor for research of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
The inclusion criteria are as follows: 1) meeting the 2010 ACR/EULAR criteria; 2) =18 years of age; and 3) DAS-28-ESR < 3.2.
The exclusion criteria are : 1) known liver disease; 2) elevated transaminases two months before the study; 3) previous history of myopathy; 4) pregnancy; 5) breastfeeding; 6) use of lipid-lowering agents; and 7) being eligible for taking lipid-lowering agents according to the National Cholesterol Education Program (NCEP).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease Activity Index. Timepoint: Before intervention, after 4 weeks, 8 weeks and 12 weeks. Method of measurement: Clinical.;Lipid profile. Timepoint: Before intervention, after 4 weeks, 8 weeks and 12 weeks. Method of measurement: Laboratory.
- Secondary Outcome Measures
Name Time Method ESR. Timepoint: Before intervention, after 4 weeks, 8 weeks and 12 weeks. Method of measurement: Laboratory.;Hs-CRP. Timepoint: Before intervention, after 4 weeks, 8 weeks and 12 weeks. Method of measurement: Laboratory.;Liver function test. Timepoint: Before intervention, after 4 weeks, 8 weeks and 12 weeks. Method of measurement: Laboratory.