NL-OMON33914已完成不适用
Genetic and environmental influences on the brain, the immunesystem and gene expression in bipolar twin pairs - a cross-sectional and longitudinal study - Brain, immune system, gene expression in BP twins
niversitair Medisch Centrum Utrecht0 个研究点目标入组 420 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 420
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Study A+B (longitudinal):
- •participation at baseline;Study A+B+C+D (cross-sectional)
- •New bipolar twin pairs
- •1) Part of a monozygotic or dizygotic twin pair
- •2) At least one twin has a diagnoses (life time) of Bipolar Disorder I or Bipolar Disorder II (DSM-IV criteria)
- •3) No history of drug or alcohol dependency (DSM-IV criteria) for the last half year
- •4) No history of Cognitive Disorder (DSM-IV criteria)
- •5) No history of serious neurological illness
- •6) No severe medical illness
- •7) Age between 18 and 60 years;New healthy control twin pairs
- •1) Part of a monozygotic or dizygotic twin pair
- •2) No history of axis I psychiatric disorder (DSM-IV criteria), on the basis of a SCID interview (Modules A-G)
- •3) No history of axis II personality disorder (DSM-IV criteria), on the basis of SIDP-V
- •4) No first degree relative with a history of specific axis I psychiatric disorder (DSM-IV criteria), on the basis of a FIGS interview
- •5) No history of drug or alcohol dependency (DSM-IV criteria) for the last half year
- •6) No history of serious neurological illness
- •7) No severe medical illness
- •8) Age between 18 and 60 years;Siblings
- •1) full sibling of an included twin pair
- •2) No history of axis I psychiatric disorder (DSM-IV criteria), on the basis of a SCID interview (Modules A-G)
- •3) No history of axis II personality disorder (DSM-IV criteria), on the basis of SIDP-V
- •4) No history of drug or alcohol dependency (DSM-IV criteria) for the last half year
- •5) No history of serious neurological illness
- •6) No severe medical illness
- •7) Age between 18 and 60 years
排除标准
- •Did not give written informed consent
- •2) Ferrous objects in or around the body (e.g. braces, glasses, pacemaker, metal fragments)
- •3) Drug or alcohol abuse over a period of six months prior to the experiment
- •4) History of closed-head injury
- •5) History of neurological illness or endocrinological dysfunction
- •6) Claustrophobia
研究者
相似试验
已完成
不适用
Gene-environment interactions in the braigezonde deelnemersN/A: healthy indivdualsNL-OMON34630Radboud Universiteit Nijmegen140
已完成
不适用
Study of influence factors that affects the brain oxygen saturation during open-heart surgeryadult patients undergoing open-heart surgeryJPRN-UMIN000017760Juntendo University100
撤回
不适用
The role of genetic, psychological and social factors in problematic alcohol drinking behavior which results in alcohol intoxication in adolescentsbinge drinking10034726alcohol intoxicationNL-OMON46320Academisch Medisch Centrum200
尚未招募
不适用
The effects of music education program of guri santa marcelina in São Paulocognitive disorderreactive child disordermental and behavior disorderF01.145.126.159F03.615.250RBR-9t7zvtniversidade estadual paulista júlio de mesquita filho
进行中（未招募）
不适用
Genetic modulation of functional brain activity of attention-deficit/hyperactivity disorder-related working memory processesEUCTR2008-006242-26-DEniversitätsklinikum Würzburg