A clinical trial to assess the clinical efficacy of functional toothpastes for improvement of periodontitis with different active ingredients
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0008981
- Lead Sponsor
- Kyung Hee University Dental Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 90
The selection criteria are as follow:
(1) Individuals aged 19 or older, both male and female with permanent teeth.
(2) Those who meet the criteria 1 or 2 of the American Society of Anesthesiologists (ASA)
(3) Those who have consented to participate in the clinical trial and voluntarily consented in writing.
(4) An individual who, through clinical examination, has at least two permanent teeth with an average probing pocket depth (PPD) of 4 mm or greater.
(5) An individual with a minimum of 20 permanent teeth.
(1) An individual with a prior history of hypersensitivity to quasi-drugs used in clinical trials or drugs from the same family.
(2) Individuals with conditions such as diabetes, HIV, heart disease, osteoporosis, and lactose intolerance.
(3) An individual who has undergone periodontal and antibiotic treatments in the past month.
(4) An individual with a history of using medications that might affect treatment outcomes, including painkillers like NSAIDs, antibiotics, or steroids, within the past week.
(5) Women who are currently pregnant or breastfeeding.
(6) A person who is a tobacco smoker.
(7) An individual who faces challenges in maintaining their oral hygiene independently.
(8) Those who encounter difficulty in comprehending and following the instructions provided in clinical studies.
(9) An individual deemed ineligible for participation in clinical trials by other evaluators.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Probing pocket depth
- Secondary Outcome Measures
Name Time Method Clinical attachment level;Gingival index;Bleeding on probing;Subgingival bacteria count