Blood pressure response to aerobic training in hypertensio

Not Applicable

• Conditions: Hypertension; CID 10 - I51

• Registration Number: RBR-3xnqxs8
• Lead Sponsor: niversidade Estadual de Campinas

Brief Summary

We tested the hypothesis that increasing exercise dose will reduce BP non-responsiveness after recommended continuous aerobic training in hypertensive patients. Hypertensive women were randomly allocated in continuous aerobic training (CAT) and control (CON). Training group cycled at moderate intensity for 12 wk and CON did not engage in exercise training. Clinic BP was evaluated before and post 12 wk. Participants classified as non-responders after CAT, remained for more 12 wk-training, increasing the exercise dose, being randomly allocated in: continuous aerobic training 3, continuous aerobic training performed 4 and high-intensity interval training. Despite SBP reduction after first 12 wk-training period, there were wide heterogeneity in inter-individual responses, with 67% of hypertensive women being non-responders to CAT. SBP and diastolic BP changes were negatively correlated with baseline values. In second 12-wk training period, after increasing exercise dose, the number of SBP non-responders reduced from 67 to 27%. In hypertensive women, traditional CAT program is not sufficient to significantly decrease BP in most people. However, individuals who are not sensitive to recommended exercise may reduce BP if they were exposed to increased exercise doses.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-03-20
• Study Start: 2022-04-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion: Female participants; postmenopausal; systolic blood pressure and diastolic blood pressure lower than 160 and 100 mmHg.

Exclusion Criteria

Exclusion: active women; cardiovascular disease besides hypertension; limiting osteoarticular diseases; use of medications that directly affect the heart rate (i.e., beta-blockers); obesity stage 2 or greater; insulin-dependent diabetes mellitus; the presence of any cardiovascular alteration at resting or exercise electrocardiogram.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A mean reduction in blood pressure greater than or equal to 1 mmHg was observed, assessed by an aneroid sphygmomanometer before and after 12 weeks of aerobic training.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not founded