A clinical trial to comparatively evaluate budesonide versus fluticasone nebulisation for prevention of post operative sore throat
- Conditions
- Health Condition 1: J00-J99- Diseases of the respiratory system
- Registration Number
- CTRI/2024/08/072501
- Lead Sponsor
- Dayanand Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Adult patient of age group 18 to 70 years.
- American Society of Anaesthesiology (ASA) physical status (PS) 1,2,3
- BMI less than 35kg/m2.
- Scheduled to undergo elective surgery lasting more than 2 hours, under General Anaesthesia (GA) using Endotracheal Tube (ETT).
- Patients who are uncooperative and unwilling to take part in study
-Patient with history of preoperative sore throat or upper respiratory tract infection
- Known allergy to budesonide or fluticasone
- Patient already on budesonide or fluticasone treatment
-Pregnant or lactating mothers
-History of COPD or Asthma
-Mallampati grade greater than 2
-Surgeries in prone position
- Patients undergoing day care, bariatric, cardiac, nasal, oral, head and neck surgeries
- Patient requiring throat pack
-Obese patients BMI greater than 35kg/m2
- Patients with history of use of steroids or NSAIDS within 24 hrs of surgery
-Patients having psychiaric illness and communication difficulties
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare incidence, severity and duration of sore throat in all 3 groupsTimepoint: To compare incidence, severity and duration of sore throat at post op hours 0, 2, 4, 8, 12, 24
- Secondary Outcome Measures
Name Time Method 1. To compare occurance of postextubation cough and hoarseness of voice in all 3 groups <br/ ><br>2. To compare side effect profile of both the drugsTimepoint: hoarseness of voice postoperatively at 0hour, 2hours, 4hours, 8hours,12 hours, 24 hours