Skip to main content
MedPathMedPath Home
Clinical Trials/TCTR20191124003
TCTR20191124003
Recruiting
未知

Association of Hypoxia Measured by Oxygen Desaturation Index (ODI) in OSA with Delis-Kaplan Executive Function System (D-KEFS) Tests in Middle-Aged and Older Adults

Chulalongkorn University0 sites29 target enrollmentNovember 24, 2019
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsObstructive sleep apneaCognitive impairmentMemoryExecutive functionElderlyMagnetic resonance imaging

Overview

Phase
未知
Intervention
Not specified
Conditions
Obstructive sleep apnea
Sponsor
Chulalongkorn University
Enrollment
29
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
November 24, 2019
End Date
December 31, 2019
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Newly diagnosed with moderate to severe OSA by a split\-night laboratory polysomnography (apnea hypopnea index ≥ 15\)

Exclusion Criteria

  • •1\.Severe systemic diseases : cirrhosis (Child\-Pugh score B or C), chronic kidney disease stage 3 or more, pulmonary disease with chronic hypoxia or hypercarbia, heart failure NYHA II or more
  • •2\.Psychiatric illness
  • •3\.Neurological diseases : brain tumor, stroke, epilepsy, coma, history loss of consciousness of more than 30 mins after head trauma, encephalitis
  • •4\.Use of psychotropic medications
  • •5\.Alcohol or illicit drug abuse
  • •6\.Prior therapy for OSA
  • •7\.Sleep disorders other than OSA including central sleep apnea, insomnia, REM behavioral disorder, restless leg syndrome, periodic limb movement disorder, narcolepsy
  • •8\.Thai Mental State Examination score \< 24
  • •9\.Inability to complete neuropsychological assessments or not fluent in Thai
  • •10\.Contraindications for MRI: presence of cardiac pacemaker or defibrillator, presence of metallic implants, claustrophobia, or uncomfortable or unable to lie down still for the MRI.

Outcomes

Primary Outcomes

Not specified

Similar Trials

Recruiting
Not Applicable
Association of Hypoxia Measured by Oxygen Desaturation Index (ODI) in OSA with Delis&#45;Kaplan Executive Function System (D&#45;KEFS) Tests in Middle&#45;Aged and Older AdultsObstructive sleep apneaCognitive impairmentMemoryExecutive functionElderlyMagnetic resonance imaging
TCTR20190805004Chulalongkorn University29
Completed
Not Applicable
Effects of oxygen status on Hypoxia Inducible Factor 1-a. A pilot proof of principle study.sepsisinfection in the blood1002766510002252
NL-OMON38504niversitair Medisch Centrum Sint Radboud20
Not yet recruiting
Not Applicable
A study on the relationship of hypoxic region and therapeutic effect in pancreatic cancerpancreatic cancer
JPRN-UMIN000041309Kyoto University25
Recruiting
Not Applicable
Identifying changes in tumour due to surgery.
CTRI/2017/10/010260Tata Memorial Hospital
Completed
Not Applicable
The relationship between hypoxic region and glucose metabolismAcute cerebral infarction, chronic crebrovascular disease, brain tumor, hypoxic encephalopathy
JPRN-UMIN000018043Kyoto University Graduate School of Medicine150