euro-cognitive effects of tyrosine supplementation in healthy older adults: A fNIRS-EEG study
Completed
- Conditions
- Aging, working memory, EEG, cerebral blood flow
- Registration Number
- NL-OMON29556
- Lead Sponsor
- Wageningen University, Division of Human Nutrition
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
Aged 60-75 years
- Right-handed
Exclusion Criteria
- Mini-Mental State Examination (MMSE) score of <24 (Folstein et al. 1975)
- Estimated IQ of <85 (based on Nederlandse Leestest voor Volwassenen (NLV) -score) (Schmand et al. 1991)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in functional prefrontal activation as determined by oxygenated hemoglobin changes (ìmol/L) induced by tyrosine supplementation, measured during response inhibition performance
- Secondary Outcome Measures
Name Time Method - Changes in functional prefrontal activation as determined by oxygenated hemoglobin changes (ìmol/L) induced by tyrosine supplementation, measured during working memory performance.<br /><br>- Changes in functional prefrontal activation as determined by deoxygenated hemoglobin changes (ìmol/L) induced by tyrosine supplementation, measured during response inhibition performance and working memory performance.<br /><br>- Changes in brain activity as determined by EEG frequency bands, induced by tyrosine supplementation, measured during response inhibition performance. <br>