The role of hormones in acute coronary syndrome (heart attack)

Not Applicable

Completed

• Conditions: Acute coronary syndrome; Circulatory System

• Registration Number: ISRCTN62480360
• Lead Sponsor: Medical University of Sofia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-06-30
• Study Start: 2023-12-18
• Last Update Posted: 8 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 175

Inclusion Criteria

Adult men and women admitted to hospital with acute coronary syndrome.

Exclusion Criteria

Acute infectious disease, any diagnosed neoplastic disease; fracture, physical trauma or surgical procedure a month before and after the inclusion period and at the end of the follow-up.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Oxidized low-density lipoproteins (oxLDL), high-sensitive C-reactive protein (hsCRP), white blood cell counts (WBC), and cardiac enzymes (creatine kinase [CK], Muscle-Brain fraction of CK [CPK-MB], high-sensitive troponin T [hsTnT]) were evaluated in plasma obtained within two hours of coronary angiography (CAG)<br>2. Coronary disease severity, measured using SYNTAX score after CAG<br>3. Total 17ß-estradiol [E2], total testosterone [T], dehydroepiandrosterone-sulfate [DHEA-S] measured using blood samples drawn 48 hours after symptom onset

Secondary Outcome Measures

Name	Time	Method
Patient information on obesity, diabetes mellitus and incidence of revascularizations, reinfarctions and deaths after one- year follow up measured using patient records.