Lidocaine Patches for Attenuating the Pain of Venipuncture Intravenous Cannulation
- Conditions
- We Focus on the Pain of Venipuncture and Intravenous Cannulation
- Interventions
- Registration Number
- NCT02061475
- Lead Sponsor
- RenJi Hospital
- Brief Summary
Venipuncture and intravenous cannulation are the most common painful procedures, especially for the penitents who must receive large diameter venous catheter before surgery. In present study we would evaluate the safety and validity of lidocaine patches releasing such pain.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 240
- Patients who want to participate present study and sign the informed consent form
- Age from 18 to 65 years old
- Patients who need intravenous cannulation before surgery
- ASA class I-II and selected patients
- Allergic to lidocaine or any other amide local anesthetics or any other medicine
- Allergic skin(allergic to past agent or other topical used medicine)
- Skin injured or inflection exist in the local site to patch
- Sensation disturbed in any limb
- Severe liver and kidney original disease:blood Aspertate aminotransferase and Alanine transaminase increased 1.5 times more than normal concentration; blood creatinine is higher than the normal range.
- Hemoglobin <80g/L
- ECG is significantly abnormal
- pregnant or possible pregnant or breastfeeding woman
- Patient who has consciousness disturbance can not make credible dialog with investigator.
- Those who are using other medicine may affect the evaluation of present patch
- Those who have participated in other clinical trail in the past three months
- Those excluded by investigator believed other reasons.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Lidocaine Patches Lidocaine Patches -
- Primary Outcome Measures
Name Time Method The efficiency of lidocaine patches for attenuating the pain of venipuncture intravenous cannulation before surgery Two minters after intravenous cannulation VAS score will be evaluated two minters after intravenous cannulation in both group with lidocaine patches or not.
Skin response after intravenous cannulation Thirty minters after intravenous cannulation Local skin response to the lidocaine patches will be evaluated thirty minters after intravenous cannulation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (8)
Guanzhou First people's Hospital
🇨🇳Guangzhou, Guangdong, China
Xiangya Hospital Central South University
🇨🇳Changhai, Hunan, China
The First Affiliate Hospital of Soochow University
🇨🇳Suzhou, Jiangsu, China
Zhongshan Hospital Affiliated to Shanghai Fudan University
🇨🇳Shanghai, Shanghai, China
Shengjing Hospital of China Medical University
🇨🇳Shenyang, Liaoning, China
Renji Hospital, School of Medicine, Shanghai Jiaotong University
🇨🇳Shanghai, Shanghai, China
Shanghai First People's Hospital
🇨🇳Shanghai, Shanghai, China
Peking University First Hospital
🇨🇳Beijing, Beijing, China