Prospective Evaluation of Volatile Sedation Management in Critical Care After Free Flap Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sedation Set-up Time
- Sponsor
- Goethe University
- Enrollment
- 34
- Locations
- 1
- Primary Endpoint
- Working time expenditure
- Status
- Completed
- Last Updated
- 12 months ago
Overview
Brief Summary
Patients undergoing complex free flap surgery are randomised to volatile or intravenous sedation in terms of subsequent intensive care sedation, based on the in-hospital standard of care. For study purposes, differences in management (set-up times, change of filters, etc.) will be investigated in relation to accelerated awakening and possibly improved neurocognition after the end of sedation.
Investigators
Armin N. Flinspach
Principal Investigator
Goethe University
Eligibility Criteria
Inclusion Criteria
- •Free flap surgery
- •Patient capable of giving informed written consent
Exclusion Criteria
- •Intolerance to volatile anaesthetics (e.g. malignant hyperthermia).
- •Severe obstructive pulmonary disease
- •Pre-existing severe neurocognitive disorder
- •Age \<18 years (minors)
Outcomes
Primary Outcomes
Working time expenditure
Time Frame: Inventory of the required time until the end of sedation (90 hours)
Time spent by nurses or physicians on the specific sedation procedure, as well as the corresponding financial value based on nationally applicable collective wage agreements in euros or US dollars.
Material consumption
Time Frame: Inventory of the required materials until the end of sedation (90 hours)
Required equipment and disposable materials related to the treatment interval as well as their monetary value in euros or US dollars.
Secondary Outcomes
- Time to awake(Within the intensive care stay (5 days))
- Delir(Within the intensive care stay (5 days))