Influence of reduction of standard preoperative fasting time and that added with protein in patients with head and neck cancer

Not Applicable

Recruiting

• Conditions: Postoperative complications; Insulin resistance; Malignant neoplasm of head, face and neck; Head and Neck Neoplasms.; C76.0; C18.452.394.968.500; C23.550.767; C04.588.443

• Registration Number: RBR-63ctjw
• Lead Sponsor: Instituto Nacional de Câncer

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-05-23
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

All patients who are candidates for elective surgeries; who are 19 years of age or older; and consent to participate in the study through the signing of the Informed Consent Form.

Exclusion Criteria

Volunteers inability to receive oral feeding in the preoperative period; without adherence to any of the phases of the study protocol; in use of prophylactic antiemetics 24 hours before surgery and in the immediate postoperative period; with previous diagnosis of diabetes mellitus, chronic kidney disease and / or liver disease, obesity (WHO, 2000); with presence of gastroesophageal reflux; intestinal obstruction and cases of gastroparesis and / or pyloric stenosis and surgeries with low nutritional impact (base of skull, maxillary sinuses, thyroid gland, parotid glands, cutaneous and ocular).

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increased muscle strength in the group receiving CHO-P, compared to the CHO group, around 10% higher, verified by assessment of palmar grip strength.

Secondary Outcome Measures

Name	Time	Method
Expected outcome 1: Reduction in response to insulin resistance, measured by the HOMA-IR and QUICKI indices, more effective in the CHO-P group with a difference of p <0.05 in relation to the CHO group.<br><br>Expected outcome 2: Lower incidence of postoperative complications, assessed by self-collected data sheet, in the CHO-P group compared to the CHO group. There is no expected reduction parameter.