rTMS in chronic depressio

Not Applicable

Completed

• Conditions: Depression; Mental and Behavioural Disorders

• Registration Number: ISRCTN15535800
• Lead Sponsor: Radboud University Nijmegen Medical Centre

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/32385741 results (added 11/05/2020) 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32663974/ (added 05/10/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-06-29
• Study Completion: 2019-11-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

1. Males and females above 18 years of age
2. Unipolar major depressive disorder without psychotic symptoms (DSM-lV), with a chronic course during the last two years
3. Treatment resistance for at least two antidepressants treatment and a form of psychotherapy

Exclusion Criteria

1. Presence of a current or past relevant somatic or neurological disorder
2. A comorbid diagnosis of bipolar disorder, schizophrenia or substance dependence disorders
3. Epilepsy, convulsion or seizure (TMS)
4. Serious head trauma or brain surgery
5. Large or ferromagnetic metal parts in the head (except for a dental wire)
6. lmplanted cardiac pacemaker or neurostimulator
7. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified