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Comparison of the effect of co2 laser versus co2 laser and PRP on periorbital hyperpigmentatio

Phase 2
Conditions
periorbital hyperpigmentation.
Disorder of pigmentation, unspecified
Registration Number
IRCT2015103118210N4
Lead Sponsor
vice chancellor of Iran University of Medical Sciences research committee
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
100
Inclusion Criteria

inclusion criteria:presence of POH;20-50 years old;women
exclusion criteria:patients with platelet function impairment;severe thrombocytopenia(less than 50000);hemodynamic unstability;chronic hematologic disease(diabetes;chronic infection and blood dyscrasia);local inflammatory skin disorder or active herpes infection in site of procedure;consuming anticoagulant drugs or NSAIDs 48 hours before procedure;consuming topical corticosteroids in site of treatment 1 month before procedure;consuming systemic corticosteroids 2 weeks before procedure;fever;cancer(specially bone marrow or hematologic);level of hemoglubin lower than 10 gr in dl.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Periorbital hyperpigmentation. Timepoint: 3 monyhs and 6 months later. Method of measurement: photography.
Secondary Outcome Measures
NameTimeMethod
ightening the periorbital skin. Timepoint: 3 months and 6 months later. Method of measurement: photography.
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