The impact of zinc supplementation on anorexia in chronic kidney disease

Phase 2

• Conditions: Anorexia; Renal and Urogenital - Kidney disease

• Registration Number: ACTRN12623000972628
• Lead Sponsor: niversity of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-09-06
• Last Update Posted: 9 October 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

(1) Aged 18 years and over,
(2) Established chronic kidney disease (review of eGFR over the previous 12 months),
(3) eGFR =<20ml/min/1.73m2 for at least 3 months, and
(4) Self-reported anorexia (poor appetite) for =/>2 consecutive weeks

Exclusion Criteria

(1) Be receiving Kidney replacement therapy (hemodialysis, peritoneal dialysis, kidney transplant),
(2) Planning to commence KRT within the next 4 months,
(3) Significant acute nutritional compromise that requires immediate nutritional intervention
(e.g., greater than or equal to 10% unintentional weight loss in the previous month and/or nutritional intake meeting less than 50% of estimated energy requirements),
(4) Confirmed or suspected non-kidney disease related cause of anorexia (defined by cytotoxic chemotherapy or head or neck radiotherapy within 3 months, or in the opinion of the investigator),
(5) Known or suspected eating disorder,
(6) Active malignancy, and
(7) Life expectancy less than 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in self-reported anorexia from baseline to 3-months. Anorexia will be measured using the Council for Nutrition Appetite Questionnaire. [ Anorexia will be measured at baseline, 3 months and 4 months post baseline. ]