Effect of Zinc in Obesity

Not Applicable

• Conditions: Overweight and obesity; Obesity.

• Registration Number: IRCT20201018049061N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

BMI> 30 kg/m2
Serum zinc < 70 mcg/dl
Appetite questionnaire score > 20

Exclusion Criteria

Vitamin and supplements use over the past 2 months
Diet or weight loss products use recently
Presence of liver, kidney, thyroid, diabetes, AIDS and other metabolic diseases
Using lipid lowering, blood-thinning and beta-blocker drugs

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum level of leptin. Timepoint: At entry and 3 month after zinc supplementation. Method of measurement: ELISA method.;Serum level of ghrelin. Timepoint: At entry and 3 month after zinc supplementation. Method of measurement: ELISA method.;Serum level of C-Reactive Protein (CRP). Timepoint: At entry and 3 month after zinc supplementation. Method of measurement: Immunoturbidimetric method.;Serum zinc consentration. Timepoint: At entry and 3 month after zinc supplementation. Method of measurement: Atomic absorption spectrometry.

Secondary Outcome Measures

Name	Time	Method
Body Mass Index (BMI). Timepoint: At entry, week 6 and 3 month after zinc supplementation. Method of measurement: Weight in Kilograms divided by height in metres squared.;Waist to Hip Ratio (WHR). Timepoint: At entry, week 6 and 3 month after zinc supplementation. Method of measurement: Waist circumference divided by hip circemference.