The effects of zinc supplementation on serum adiponectin level and insulin resistance in patients with type II diabetes mellitus
- Conditions
- diabetes mellitus type 2.Non-insulin dependent diabetes mellitus
- Registration Number
- IRCT138811013128N1
- Lead Sponsor
- Endocrinology & Metabolism Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Age between 30 to 50 years, presence of type 2 diabetes at least for one year, willingness to participate in the study and sign the informed consent, BMI=25-30, HbA1C=8.5, Blood pressure =135/85 mmHg. Exclusion criteria: severe kidney, heart, liver, GI, pulmonary and infectious diseases, thyroid dysfunction, active cancer, previous myocardial infarction, recent surgery, Insulin therapy, changing in dose of medications such as oral anti-diabetic, anti-lipidemic and anti-hypertensive drugs 3 month before and during the study, consumption of vitamin-mineral supplements 6 month before and during the study, consumption of non-steroidal anti inflammatory drugs, glucocorticoids, hormonal drugs, antidepressants, psychotropic medications, antibiotics, dioretics, three months prior to study, Following weight-reducing diet 3 months before and during the study, smoking, pregnancy, breast feeding, postmenopausal women.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma adiponectin. Timepoint: Baseline and after 12 weeks. Method of measurement: ELISA assay.
- Secondary Outcome Measures
Name Time Method