Compassionate Use of Pennsaid Topical Lotion (Diclofenac) in Osteo or Rheumatoid Arthritis
- Conditions
- Osteoarthritis of the Hand
- Registration Number
- NCT01579890
- Lead Sponsor
- Mallinckrodt
- Brief Summary
This was a compassionate use, open treatment safety study of Pennsaid topical lotion (diclofenac) for osteo or rheumatoid arthritis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- APPROVED_FOR_MARKETING
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- diagnosed osteo or rheumatoid arthritis
- Oral NSAIDs were not deemed appropriate treatment
- Completed diclofenac sensitivity patch test with negative result
- Signed informed consent form
Exclusion Criteria
- At the discretion of the physician and HPB
Study & Design
- Study Type
- EXPANDED_ACCESS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie diclofenac's anti-inflammatory effects in topical arthritis treatments?
How does Pennsaid's efficacy compare to standard-of-care NSAIDs for hand osteoarthritis and rheumatoid arthritis?
Are biomarkers like synovial fluid cytokine levels predictive of response to topical diclofenac in arthritic conditions?
What are the long-term safety concerns and cutaneous adverse event management strategies for Pennsaid compassionate use?
What combination therapies or alternative NSAIDs (e.g., capsaicin) are being explored for arthritis pain management alongside Mallinckrodt's programs?