Characterization and evaluation of the effectiveness of CO2 laser along with human umbilical cord blood serum alginate hydrogel compared to CO2 laser alone in facial skin rejuvenatio
Phase 1
- Conditions
- Skin rejuvenation.Other specified disorders of the skin and subcutaneous tissue related to radiationL59.8
- Registration Number
- IRCT20221130056672N8
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Men and women aged 30 to 50 with skin type II to IV who have referred for facial skin rejuvenation in the eye area.
People who have not had cosmetic intervention on their face such as botox, dermabrasion, chemical peeling and face lift in the last 6 months.
Exclusion Criteria
People who have received oral isotretinoin in the past 6 months and have a history of keloids.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improving repair. Timepoint: All sessions: days 0, 7, 14 and 90. Method of measurement: Skin imaging with Visioface device.;Skin moisture level. Timepoint: All sessions: days 0, 7, 14 and 90. Method of measurement: Corneometer device.;Inflammation and redness. Timepoint: All sessions: days 0, 7, 14 and 90. Method of measurement: Colorimeter and Mexameter Devices.;The amount of skin collagen. Timepoint: Before the CO2 laser, one month and three months later. Method of measurement: Cutometer device.
- Secondary Outcome Measures
Name Time Method The amount of pain. Timepoint: Days 0, 7, 14 and 90. Method of measurement: Questionnaire survey (Patient self-report).