ASSOCIATION OF BIOMARKERS IN GCF OF HEALTH, GINGIVITIS, PERIODONTITIS
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2023/01/049155
- Lead Sponsor
- Madhulika K
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Individuals with healthy periodontium.
2. Patients with diagnosis of generalized gingivitis
3. Patients with diagnosis of generalized stage III grade B periodontitis
(Periodontal health, gingivitis and periodontitis definition will be based on the classification of periodontal and peri-implant diseases and conditions as proposed in 2017 World Workshop)
4. Individuals with type 2 diabetes mellitus (HbA1c < 7.0%)
5. Presence of at least 20 natural teeth
1. Obese individuals, BMI >25 kg/m2 , waist circumference of >= 90 cm for men and >= 80cm for women according to Asian Pacific Perspective Obesity-WHO 2000.
2. Individuals who have received periodontal therapy in the last 6 months.
3. Individuals with systemic diseases other than type 2 diabetes mellitus (HbA1c < 7.0%)
4. Individuals who have history of antimicrobial and anti-inflammatory therapy
5. Smokers
6. Pregnant/lactating and postmenopausal women
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Biomarkers Ghrelin and OsteocalcinTimepoint: Before treatment
- Secondary Outcome Measures
Name Time Method Ghrelin and osteocalcinTimepoint: Before treatment