Role of pulmonary collectins and antimicrobial peptides in patients with pulmonary nontuberculous mycobacteria disease
Not Applicable
- Conditions
- Pulmonary nontuberculous mycobacterial disease
- Registration Number
- JPRN-UMIN000027652
- Lead Sponsor
- Division of Respiratory Medicine, National Hospital Organization Kyoto Medical Center
- Brief Summary
The KCQ revealed that the proportion of frail NTM patients at diagnosis was higher than that of frail BE patients (48.5% vs. 22.2%, p = 0.026). HADS scores were significantly higher in the NTM group than in the BE group (p < 0.01). Bronchoalveolar lavage fluid (BALF) hCAP/LL-37 and SP-D levels were significantly higher (p = 0.001), but serum hCAP/LL-37 levels were significantly lower in the NTM group than in the BE group (p = 0.023).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 69
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with HIV infection or disseminated MAC infection, without CRT scan data are excluded. Patients whose observational time is less than 12 months.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method