Analysis of Bronchoalveolar Lavage to Assess Local Immunopathology
Not Applicable
- Conditions
- Severe Pneumonia
- Registration Number
- JPRN-UMIN000046236
- Lead Sponsor
- PERPARI - Indonesian Respirology Society
- Brief Summary
There was a significance difference on local immunopathology response of CD4 BAL between right and left lung of severe pneumonia patients (p = 0,003). There was a significance difference of CD4 BAL in severely affected lung on extubation 19 days (p = 0,01) and mortality 28 days (p = 0,004). There were kinetic interactions between alveolar macrophage function, IL-6, IL-17, CD4, and Treg in severely affected lung on the extubation and mortality status.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
non-infectious acute respiratory distress syndrome, HIV/AIDS, active malignancy within 12 months, under immunosuppressants, refuse to undergo bronchoscopy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method