PREG-MS: New England MS Pregnancy Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 168
- 试验地点
- 1
- 主要终点
- The relationship between EDSS and pregnancy course
研究概览
简要总结
The purpose of the study is to develop a detailed pregnancy registry of patients with Multiple Sclerosis in the New England states. Women with a diagnosis of MS that are either pregnant or actively planning to become pregnant are eligible to participate.
The study will solely take place through phone interviews. One of the study coordinator at the Partners MS Center will contact the participant for an intake phone interview where general information about the individual, their pregnancy and their MS will be collected. Thereafter the coordinator will contact the participant every 3 months for 20 minutes follow up interviews. After birth, the coordinator will collect information on the growth and development of the participant's baby. Pediatric interviews will be conducted at 2, 4, 6, 9, 12, 18, 24, 36 months. Information from the participant's neurologist and obstetrician, as well as information from the baby's pediatrician, will be made available to the study staff at regular intervals throughout the duration of the study.
Through this study, the investigators hope to learn more about the effects of MS on pregnancy and pediatric development, and about the effects of pregnancy on the course of MS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Multiple Sclerosis;
- •Pregnant or actively planning to become pregnant.
排除标准
- 未提供
结局指标
主要结局
The relationship between EDSS and pregnancy course
时间窗: 9 months
The investigators assessed the correlation between EDSS scores and the presence of pregnancy complications, or the lack thereof.
次要结局
- The relationship between MS treatments and pregnancy course(9 months)
研究者
Maria Houtchens
Assistant Professor of Neurology
Brigham and Women's Hospital
