Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Respiratory Failure
- Sponsor
- Massachusetts General Hospital
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Endotracheal intubation during present hospitalization, recorded through chart review
- Status
- Terminated
- Last Updated
- 6 months ago
Overview
Brief Summary
This study uses the AirGo band to monitor changes in tidal ventilation in spontaneously breathing patients with COVID-19 associated respiratory failure. It aims to recognize patterns of ventilation associated with worsening respiratory failure in this patient population. If successful, this study will lead to the development of new robust methods for real-time, continuous monitoring of respiratory function in patients with respiratory failure. In turn, such monitoring methods may enable improvements in the medical management of respiratory failure and timing of interventions.
Investigators
Omar Hyder
Anesthesia & Critical Care Attending Physician
Massachusetts General Hospital
Eligibility Criteria
Inclusion Criteria
- •Admitted to the hospital
- •≥ 18 years of age
- •Clinically suspected or confirmed COVID-19 infection
- •Spontaneously breathing
- •For patients not on supplemental oxygen at their location of residence prior to hospital admission, need for supplemental O2 to maintain SpO2 \>=92%
- •For patients on supplemental O2 at their location of residence prior to hospital admission, an increase in requirement of supplemental oxygen from baseline
Exclusion Criteria
- •Intubated patients
- •Pregnant women
- •Moribund patients
- •Patients who are on comfort measures (CMO)
Outcomes
Primary Outcomes
Endotracheal intubation during present hospitalization, recorded through chart review
Time Frame: Up to three weeks
Progression of respiratory failure to require endotracheal intubation (and mechanical ventilation)
Secondary Outcomes
- Premature need for removal of the band, recorded through investigator report(Up to three weeks)
- Improvement in hypoxemia as indicated by oxygen saturation and requirement for supplemental oxygen, recorded through chart review(Up to three weeks)
- In-hospital mortality, recorded through chart review(Up to 24 weeks)